Spatiotemporal dynamics of successive activations across the human brain during simple arithmetic processing.
Pedro Pinheiro-ChagasClara Sava-SegalSerdar AkkolAmy L DaitchJosef ParviziPublished in: bioRxiv : the preprint server for biology (2023)
Our study elucidates the spatiotemporal dynamics and anatomical specificity of brain activations across >10,000 sites during arithmetic tasks, as captured by intracranial EEG. We discovered an orderly, successive activation of brain regions, consistent across individuals, and a decrease in functional connectivity as a function of temporal distance between regions. Our findings provide unprecedented insights into the sequence of cognitive processing and regional interactions, offering a novel perspective for enhancing computational models of cognitive symbolic systems.