Pathogenic variants among females with breast cancer and a non-breast cancer reveal opportunities for cancer interception.

Brittany L BychkovskyMin-Tzu LoAmal YussufCarrie HortonParichehr HemyariHolly LaDucaJudy E GarberRochelle ScheibHuma Q Rana

Published in: Breast cancer research and treatment (2023)

Females with MPC, including BC, have a high frequency of germline PVs (14.1%). These data delineate the opportunities for intercepting subsequent cancers associated with genetic risk among females diagnosed first with BC.

Keyphrases

high frequency
transcranial magnetic stimulation
genome wide
copy number
papillary thyroid
childhood cancer
electronic health record
squamous cell
dna repair
single cell
gene expression
deep learning