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Unique Associations of DNA Methylation Regions With 24-Hour Blood Pressure Phenotypes in Black Participants.

Michelle L RobertsTheodore A KotchenXiaoqing PanYingchuan LiChun YangPengyuan LiuTao WangPurushottam W LaudThomas H CheliusYannick MunyuraDavid L MattsonYong LiuAllen W CowleySrividya KidambiMingyu Liang
Published in: Hypertension (Dallas, Tex. : 1979) (2022)
We identified several MRs that explain a substantial portion of variances in 24-hour BP phenotypes, which might be excellent markers of cumulative effect of factors influencing 24-hour BP levels. The Bisulfite ULtrapLEx Targeted Sequencing workflow has potential to be suitable for clinical testing and population screenings on a large scale.
Keyphrases
  • blood pressure
  • dna methylation
  • hypertensive patients
  • heart rate
  • genome wide
  • single cell
  • type diabetes
  • metabolic syndrome
  • electronic health record
  • climate change
  • drug delivery