Distinct genetic landscape and a low response to doxorubicin in a luminal-A breast cancer cell line of Pakistani origin.

Muhammad ShakeelSalman Ahmed KhanAnum Jabeen MughalMuhammad IrfanDaniel C HoessliM Iqbal ChoudharyMuhammad AurongzebIshtiaq Ahmad Khan

Published in: Molecular biology reports (2021)

This study presents a distinct genetic architecture in luminal-A breast cancer potentially responsible for differential response to chemotherapy. Further studies on large cohorts of breast cancer patients are suggested for implementation in personalized medicine.

Keyphrases

genome wide
primary care
healthcare
copy number
single cell
case control
breast cancer risk
rectal cancer