Chronic Hypoxia in Ovine Pregnancy Recapitulates Physiological and Molecular Markers of Preeclampsia in the Mother, Placenta, and Offspring.

Wen Tong Beth A Allison Kirsty L BrainOlga V PateyYouguo NiuKimberley J BottingSage G FordTessa A GarrudPeter F B Wooding Caroline J ShawQiang LyuLin ZhangJin MaTereza Cindrova-DaviesHong Wa YungGraham J Burton Dino A Giussani

Published in: Hypertension (Dallas, Tex. : 1979) (2022)

Therefore, we show in an ovine model of sea-level adverse pregnancy that chronic hypoxia recapitulates physiological and molecular features of preeclampsia in the mother, placenta, and offspring.

Keyphrases

pregnancy outcomes
early onset
high fat diet
preterm birth
endothelial cells
pregnant women
single molecule
type diabetes
emergency department
adipose tissue