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Clinical translational neuroimaging of the antioxidant effect of N-acetylcysteine on neural microstructure.

Sue Y YiBrian R BarnettMcKenzie J PoetzelNicholas A StoweJohn Paul J Yu
Published in: Magnetic resonance in medicine (2021)
These findings provide evidence for a treatment pathway targeting endogenous antioxidant capacity, and the clinical translational utility of neurite orientation dispersion and density imaging microstructural imaging to sensitively detect microstructural alterations resulting from antioxidant treatment.
Keyphrases
  • white matter
  • high resolution
  • oxidative stress
  • anti inflammatory
  • combination therapy
  • cancer therapy
  • mass spectrometry