Anti-A/B isoagglutinin reduction in an intravenous immunoglobulin product and risk of hemolytic anemia: a hospital-based cohort study.

Christopher WallenhorstAmi PatelAmgad SheblAlphonse HubschToby L SimonCarlos Martinez

Published in: Transfusion (2020)

Implementation of immunoaffinity chromatography in Privigen manufacturing resulted in a significant 90% reduction of HA risk. HA has become a rare event in association with Privigen use.

Keyphrases

healthcare
mass spectrometry
primary care
chronic kidney disease
high speed
high dose
quality improvement
liquid chromatography
acute care
adverse drug
low dose
breast cancer risk