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Biallelic mutations in EXOC3L2 cause a novel syndrome that affects the brain, kidney and blood.

Adel ShalataSupanun LauhasurayotinZvi LeibovitzHongbing LiDiane HebertSanthosh DhanrajYarin HadidMohammed MahroumJacob BajarSandro EgenburgAyala AradMordechai ShohatSami HaddadHassan BakryHoutan MoshiriStephen W SchererShay TzurYigal Dror
Published in: Journal of medical genetics (2018)
We propose that biallelic EXOC3L2 mutations lead to a novel syndrome that affects hindbrain development, kidney and possibly the bone marrow.
Keyphrases
  • bone marrow
  • intellectual disability
  • case report
  • mesenchymal stem cells
  • autism spectrum disorder
  • brain injury
  • blood brain barrier
  • functional connectivity