Radiation-Induced Coronary Artery Disease and Its Treatment: A Quick Review of Current Evidence.
Christopher DeZorziPublished in: Cardiology research and practice (2018)
As advances in medical technology arise and the availability of cancer treatment increases, an increased number of patients are receiving cancer treatment. Radiation therapy has evolved to become one of the cornerstones of treatment for various types of cancers. One of the long-term consequences of radiation therapy is radiation-induced coronary artery disease (RICAD). Although the pathophysiology of RICAD may be slightly different and more acute onset than the commonly seen "generic" coronary artery disease, it is common practice to treat RICAD in the same method as nonradiation-induced CAD. This paper summarizes the current research available on the topic and shows there is not enough research to obtain significant data about outcomes and restenosis rates of PCI or outcomes of CABG in RICAD. The aim of this review is to create a concise and easy-to-follow review of the relevant data regarding RICAD and hopefully spark further interest in future studies in this field.
Keyphrases
- radiation induced
- coronary artery disease
- radiation therapy
- coronary artery bypass grafting
- percutaneous coronary intervention
- cardiovascular events
- healthcare
- electronic health record
- acute coronary syndrome
- ejection fraction
- end stage renal disease
- primary care
- artificial intelligence
- prognostic factors
- st segment elevation myocardial infarction
- type diabetes
- oxidative stress
- data analysis
- st elevation myocardial infarction
- respiratory failure
- squamous cell carcinoma
- left ventricular
- high glucose
- current status
- patient reported outcomes
- metabolic syndrome
- heart failure
- aortic valve
- glycemic control
- adipose tissue
- coronary artery bypass
- aortic dissection
- machine learning
- endothelial cells