Rethinking Carbapenems: A Pharmacokinetic Approach for Antimicrobial Selection in Infected Necrotizing Pancreatitis.

Christina MaguireDeepak AgrawalMitchell J DaleyElizabeth DouglassDusten T Rose

Published in: The Annals of pharmacotherapy (2020)

Noncarbapenem antipseudomonals, such as piperacillin/tazobactam and cefepime, are appropriate carbapenem-sparing options in INP, based on PK data, spectrum of activity, and risk of collateral damage.

Keyphrases

gram negative
klebsiella pneumoniae
acinetobacter baumannii
multidrug resistant
staphylococcus aureus
electronic health record
oxidative stress
robot assisted
big data
escherichia coli