The role of the oncostatin M/OSM receptor β axis in activating dermal microvascular endothelial cells in systemic sclerosis.

G MardenQ WanJ WilksK NevinM FeeneyN WisniackiM TrojanowskiA BujorL StawskiMaria Trojanowska

Published in: Arthritis research & therapy (2020)

This work provides new insights into the role of the OSM/OSMRβ axis in activation/injury of dermal ECs and supports the involvement of this pathway in SSc vascular disease.

Keyphrases

systemic sclerosis
interstitial lung disease
endothelial cells
signaling pathway
wound healing
rheumatoid arthritis
vascular endothelial growth factor