Direct Oral Anticoagulants for Treating Acute Venous Thromboembolism in Children: Meta-Analysis of Randomized Controlled Trials.

Xin YuWengen ZhuChen LiuRenrong Lu

Published in: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis (2024)

DOACs, primarily dabigatran and rivaroxaban, are non-inferior to standard anticoagulants in reducing VTE recurrence in pediatric patients, with comparable safety profiles. Further research is essential to confirm these findings.

Keyphrases

venous thromboembolism
direct oral anticoagulants
liver failure
atrial fibrillation
systematic review
young adults
respiratory failure
drug induced
aortic dissection
free survival
intensive care unit
acute respiratory distress syndrome
mechanical ventilation