Frontal and occipital brain glutathione levels are unchanged in autistic adults.

Andreia C PereiraAlison LeonardHester VelthuisNichol M L WongFrancesca M PonteduroMihail DimitrovClaire L EllisLukasz KowalewskiDavid J LythgoeDiana-Georgina RotaruRichard A E EddenGlynis IvinCharlotte M PretzschEileen DalyDeclan G M MurphyGráinne M McAlonan

Published in: PloS one (2024)

GSH levels as measured using 1H-MRS are unaltered in the DMPFC and mOCC regions of autistic adults, suggesting that oxidative stress in these cortical regions is not a marked neurobiological signature of ASD.

Keyphrases

oxidative stress
autism spectrum disorder
resting state
functional connectivity
white matter
attention deficit hyperactivity disorder
dna damage
working memory
ischemia reperfusion injury
intellectual disability
fluorescent probe
diabetic rats