Role of IL-13Rα2 in modulating IL-13-induced MUC5AC and ciliary changes in healthy and CRSwNP mucosa.
Jing LiuY Y LiA K AndiappanY YanK S TanH H OngK T ThongY K OngF G YuH B LowY L ZhangL ShiDe Yun WangPublished in: Allergy (2018)
IL-13Rα2 has a potential role in IL-13-induced MUC5AC and ciliary changes through ERK1/2 signal pathway in the nasal epithelium. IL-13Rα2 may contribute to airway inflammation and aberrant remodeling which are the main pathological features of CRSwNP.