Heterogeneity within and between physician-diagnosed asthma and/or COPD: NOVELTY cohort.

Helen K Reddel Jorgen Vestbo Alvar AgustíGary P AndersonAruna T Bansal Richard Beasley Elisabeth H Bel Christer Jansson Barry J MakeIan D PavordDavid J PriceEleni RapsomanikiNiklas KarlssonDonna K FinchJavier NuevoAlex de Giorgio-MillerMarianna AlacquaRod HughesHana MüllerováMaria Gerhardsson de Verdiernull null

Published in: The European respiratory journal (2021)

This analysis demonstrates marked heterogeneity within, and overlap between, physician-assigned diagnosis and severity groups in patients with asthma and/or COPD. Current diagnostic and severity classifications in clinical practice poorly differentiate between clinical phenotypes that may have specific risks and treatment implications.

Keyphrases

chronic obstructive pulmonary disease
lung function
clinical practice
primary care
emergency department
cystic fibrosis
single cell
air pollution
allergic rhinitis
human health
climate change
combination therapy