The Potential Use of Vitamin C to Prevent Kidney Injury in Patients with COVID-19.
Feng XuYawei WenXinge HuTiannan WangGuoxun ChenPublished in: Diseases (Basel, Switzerland) (2021)
The newly found SARS-CoV-2 has led to the pandemic of COVID-19, which has caused respiratory distress syndrome and even death worldwide. This has become a global public health crisis. Unfortunately, elders and subjects with comorbidities have high mortality rates. One main feature of COVID-19 is the cytokine storm, which can cause damage in cells and tissues including the kidneys. Here, we reviewed the current literature on renal impairments in patients with COVID-19 and analyzed the possible etiology and mechanisms. In addition, we investigated the potential use of vitamin C for the prevention of renal injury in those patients. It appears that vitamin C could be helpful to improve the outcomes of patients with COVID-19. Lastly, we discussed the possible protective effects of vitamin C on renal functions in COVID-19 patients with existing kidney conditions.
Keyphrases
- sars cov
- coronavirus disease
- public health
- respiratory syndrome coronavirus
- end stage renal disease
- newly diagnosed
- induced apoptosis
- ejection fraction
- systematic review
- chronic kidney disease
- machine learning
- prognostic factors
- peritoneal dialysis
- gene expression
- human health
- cell cycle arrest
- type diabetes
- cardiovascular disease
- adipose tissue
- deep learning
- cell death
- metabolic syndrome
- mass spectrometry
- endoplasmic reticulum stress
- glycemic control