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Fasting pancreatic polypeptide predicts incident microvascular and macrovascular complications of type 2 diabetes: An observational study.

Amir H SamAdam J BuckleyBrian Y H LamGavin A BewickPaul R BechKarim MeeranMaha T BarakatStephen R BloomGiles S H YeoNader G LessanKevin G Murphy
Published in: Diabetes/metabolism research and reviews (2024)
Elevated fasting PP is independently associated with vascular complications of diabetes and affects retinal pathways potentially influencing retinal neuronal survival. Our results suggest possible new roles for PP-fold peptides in the pathophysiology of diabetes complications and vascular risk stratification.
Keyphrases
  • cardiovascular disease
  • type diabetes
  • risk factors
  • blood glucose
  • diabetic retinopathy
  • glycemic control
  • insulin resistance
  • blood pressure
  • adipose tissue
  • skeletal muscle
  • amino acid