Phenotype, Function, and Clinical Significance of CD26+ and CD161+Tregs in Splenic Marginal Zone Lymphoma.

Xinyi TangZhi-Zhang YangHyo Jin KimTheodora AnagnostouYue YuXiaosheng WuJun ChenJordan E KrullKerstin WenzlPatrizia Mondello Vaishali BhardwajJunwen WangAnne J NovakStephen M Ansell

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)

IL2/STAT5-mediated expansion of CD26+Tregs contributes to a poor clinical outcome in SMZL and may represent a therapeutic opportunity in this disease.

Keyphrases

nk cells
diffuse large b cell lymphoma
cell proliferation