Association of the CAV1-CAV2 locus with normal-tension glaucoma in Chinese and Japanese.
Shi Yao LuShi Song RongZhenggen WuChukai HuangKenji MatsushitaTsz Kin NgChristopher K S LeungRumi KawashimaShinichi UsuiPancy O S TamMotokazu TsujikawaAlvin L YoungMingzhi ZhangJaney L WiggsKohji NishidaClement C ThamChi Pui PangGuy L J ChenPublished in: Clinical & experimental ophthalmology (2020)
In this study, we confirmed the association of rs4236601 at the CAV1-CAV2 locus with NTG in Chinese. SNP rs4236601 is monomorphic, and rs1052990 tends towards a different direction in the Japanese cohort. Further studies are warranted to verify the ethnic difference and gender-specific effects of this locus.