Serum levels of irisin and nesfatin-1 in multiple sclerosis.
Mustafa AltaşAli Ulvi UcaTuran AkdağFaruk Omer OdabasOsman Serhat TokgozPublished in: Arquivos de neuro-psiquiatria (2022)
The present study revealed lower irisin and nesfatin-1 levels in patients with RRMS. These findings suggest that the decreased levels of irisin and nesfatin-1 peptides may contribute to MS pathogenesis such as inflammation, oxidative stress, and apoptosis in MS, leading to demyelination, axonal damage with neuronal loss, and gliosis.
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