Synergistic Benefits of Combined Aerobic and Cognitive Training on Fluid Intelligence and the Role of IGF-1 in Chronic Stroke.
Michelle PloughmanGail A EskesLiam P KellyMegan C KirklandAugustine J DevasahayamElizabeth M WallackBeraki AbrahaS M Mahmudul HasanMatthew B DownerLaura KeelerGraham WilsonElaine SkeneIshika SharmaArthur R ChavesMarie E CurtisEmily BedfordGeorge S RobertsonCraig S MooreJason McCarthyMarilyn Mackay-LyonsPublished in: Neurorehabilitation and neural repair (2019)
Aerobic exercise combined with cognitive training improved fluid intelligence by almost 50% in patients >6 months poststroke. Participants with more robust improvements in cognition were able to upregulate higher levels of serum IGF-1 suggesting that this neurotrophin may be involved in behaviorally induced plasticity.
Keyphrases
- end stage renal disease
- ejection fraction
- chronic kidney disease
- newly diagnosed
- atrial fibrillation
- prognostic factors
- high glucose
- binding protein
- virtual reality
- drug induced
- pi k akt
- diabetic rats
- oxidative stress
- patient reported outcomes
- cancer therapy
- growth hormone
- signaling pathway
- mild cognitive impairment
- multiple sclerosis
- cell proliferation
- drug delivery
- upper limb
- cerebral ischemia