Effect of xanthan gum-based food thickeners on the dissolution profile of fluoroquinolones oral formulations.
Nobuyuki TakahashiYoshiaki FujitaNanako TakahashiAkihiro NakamuraTsutomu HaradaPublished in: Journal of pharmaceutical health care and sciences (2020)
The effect of XG-FTs on the dissolution profile of film-coated fluoroquinolone formulations varied depending on the formulation. The CPFX formulation formed a gel-like precipitate when immersed in XG-FTs resulting in a significantly delayed dissolution.