Seroreversion to Chlamydia trachomatis Pgp3 antigen among children in a hyperendemic region of Amhara, Ethiopia.
Christine TedijantoSolomon AragieSarah GwynDionna M WittbergTaye Zeru TadegeZerihun TadesseAmbahun ChernetIsabel J B ThompsonScott D NashThomas M LietmanDiana L MartinJeremy David KeenanBenjamin F ArnoldPublished in: The Journal of infectious diseases (2023)
Monitoring trachoma transmission with antibody data requires characterization of decay in IgG to Chlamydia trachomatis antigens. In a three-year longitudinal cohort in a high transmission setting, we estimated a median IgG half-life of 3 years and a seroreversion rate of 2.5 (95% CI: 1.6, 3.5) per 100 person-years.
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