Experimental validation of the prestretch-strain relationship as a non-invasive index of left ventricular myocardial contractility.
Oana MireaCarolina VallecillaPiet ClausFrank E RademakersJan D'hoogePublished in: PloS one (2020)
The slope of the PreS-S relationship is sensitive to changes in inotropy and is less load-dependent than conventional non-invasive parameters of left ventricular function. The magnitude of the change of this slope correlates well with changes in invasive contractility measurements making it an attractive parameter to assess contractile reserve or contractile changes during longitudinal follow-up of patients.
Keyphrases
- left ventricular
- smooth muscle
- end stage renal disease
- ejection fraction
- heart failure
- aortic stenosis
- skeletal muscle
- hypertrophic cardiomyopathy
- acute myocardial infarction
- newly diagnosed
- chronic kidney disease
- cardiac resynchronization therapy
- mitral valve
- prognostic factors
- peritoneal dialysis
- left atrial
- coronary artery disease
- percutaneous coronary intervention
- acute coronary syndrome
- patient reported