Understanding the roles of glutamine synthetase, glutaminase, and glutamate decarboxylase autoantibodies in imbalanced excitatory/inhibitory neurotransmission as etiological mechanisms of autism.

Najat O HamedLaila Al-AyadhiMohamed A OsmanAbdalla O ElkhawadHanan QasemMajida Al-MarshoudNada M MerghaniAfaf El-Ansary

Published in: Psychiatry and clinical neurosciences (2018)

The obtained data indicate that GS and GLS1 are promising indicators of a neuronal excitation and inhibition system imbalance and that combined measured parameters are good predictive biomarkers of autism.

Keyphrases

autism spectrum disorder
intellectual disability
systemic lupus erythematosus
electronic health record
big data
machine learning
deep learning