Proteome profiling of salivary small extracellular vesicles in glioblastoma patients.
Juliana Muller BarkLucas Trevisan França de LimaXi ZhangDaniel BroszczakPaul J LeoRosalind L JeffreeBenjamin ChuaBryan W DayChamindie PunyadeeraPublished in: Cancer (2023)
This study, for the first time, demonstrates the feasibility of isolating and characterizing small EVs from pre- and postoperative saliva samples from GBM patients. Preliminary findings encourage further large cohort validation studies on salivary small EVs to evaluate prognosis in GBM.