Chronic Liver Enzyme Elevation and Use of Contemporary ARVs Among People With HIV.

Ashley O RoenLars PetersGilles WandelerMarc van der ValkRobert ZangerleHuldrych F GünthardFerdinand WitCristina MussiniStéphane De WitAntonella d'Arminio MonforteJörg Janne VehreschildAntonella CastagnaNadine JaschinskiVani VannappagariLinda ChenJoan TalladaJohn C'marAmanda MocroftLene Ryom

Published in: Open forum infectious diseases (2024)

cLEE is common and more frequent during the first year after initiating new ARVs. With a >5-year median follow-up, we found no short-term liver safety concerns with the use of INSTIs. Use of NNRTIs and TDF was associated with an increased cLEE risk, while DRV was associated with lower risk.

Keyphrases

antiretroviral therapy
hiv infected
hiv positive
hepatitis c virus
hiv testing
south africa