Different effects of low muscle mass on the risk of non-alcoholic fatty liver disease and hepatic fibrosis in a prospective cohort.

Hun Jee ChoeHyunsuk LeeDongHo LeeSoo-Heon KwakBo Kyung Koo

Published in: Journal of cachexia, sarcopenia and muscle (2022)

Both lower muscle mass index and genetic risk variants are important contributors to the development of NAFLD. In patients already diagnosed with NAFLD, however, PNPLA3 confers a greater risk for hepatic fibrosis progression than lower muscle mass.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
copy number
peritoneal dialysis
prognostic factors
gene expression
dna methylation