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Hypoxia and hyperglycaemia determine why some endometrial tumours fail to respond to metformin.

Vanitha N SivalingamAyşe LatifSarah KitsonRhona McVeyKatherine G FineganKay MarshallMichael P LisantiFederica SotgiaIan J StratfordEmma J Crosbie
Published in: British journal of cancer (2019)
Understanding the metabolic adaptations of endometrial tumours may identify patients likely to derive clinical benefit from metformin.
Keyphrases
  • end stage renal disease
  • newly diagnosed
  • peritoneal dialysis
  • prognostic factors
  • endometrial cancer
  • endothelial cells