Comparative neuroprotective effects of royal jelly and its unique compound 10-hydroxy-2-decenoic acid on ischemia-induced inflammatory, apoptotic, epigenetic and genotoxic changes in a rat model of ischemic stroke.

Cansu KocCigdem Inci AydemirBerna SalmanAysen CakirNursel Hasanoglu AkbulutPinar Levent KarabarutGonca TopalAycan Yigit CinarGokce TanerOzhan EyigorMehmet Cansev

Published in: Nutritional neuroscience (2024)

Our findings suggest that neuroprotective effects of RJ in experimental stroke can mostly be attributed to 10-HDA.

Keyphrases

atrial fibrillation
cell death
high glucose
cerebral ischemia
diabetic rats
dna methylation
oxidative stress
gene expression
drug induced
umbilical cord
anti inflammatory
blood brain barrier