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MRSA strains with distinct accessory genes predominate at different ages in cystic fibrosis.

Harry S PorterfieldLucas J MaakestadMason M LaMarcheAndrew L ThurmanZoe E KienenbergerNicholas J PitcherAlexis R HansenChristian F ZirbesLinda BoykenBethany L MuyskensAlejandro A PezzuloSachinkumar B SinghErik TwaitBradley FordDaniel J DiekemaValérie ReebAnthony J Fischer
Published in: Pediatric pulmonology (2021)
In this CF cohort, we identified MRSA subtypes that predominate at different ages and differ by accessory gene content. The most prevalent cluster of MRSA, including ST5 and ST105, was associated with lower FEV1 . ST8 MRSA was more common in younger patients and thus has the potential to rise in prevalence as these patients age.
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