Pyviko: an automated Python tool to design gene knockouts in complex viruses with overlapping genes.

Published in: BMC microbiology (2017)

Pyviko is an extensible and intuitive Python tool for designing knockouts of overlapping genes. Freely available as both a Python package and a web-based interface ( http://louiejtaylor.github.io/pyViKO/ ), Pyviko simplifies the experimental design of gene knockouts in complex viruses with overlapping genes.

Keyphrases

genome wide identification
genome wide
genome wide analysis
copy number
transcription factor
bioinformatics analysis
dna methylation
gene expression
genetic diversity