Docetaxel-loaded pH/ROS dual-responsive nanoparticles with self-supplied ROS for inhibiting metastasis and enhancing immunotherapy of breast cancer.

Yu WangQianmei WangXiaowen WangPu YaoQing DaiXiaowei QiMing YangXiao ZhangRong HuangJing YangQian WangPeiyuan XiaDinglin Zhang Fengjun Sun

Published in: Journal of nanobiotechnology (2023)

Our results demonstrated that DTX/FA-CA-Oxi-αCD NPs displayed great potential in preventing tumor metastasis, inhibiting tumor growth, and improving the efficacy of anti-PD-1antibody.

Keyphrases

signaling pathway
cell death
dna damage
cancer therapy
reactive oxygen species
drug delivery
radiation therapy
oxidative stress
risk assessment
young adults
wound healing
climate change