Pulmonary herpes simplex virus and cytomegalovirus in patients with acute respiratory distress syndrome related to COVID-19.

Leonoor S BoersFrank van Someren GréveJarne M van HattemJustin de BrabanderTom ZwaanHugo van WilligenMarion CornelissenMenno de JongTom van der PollJanWillem DuitmanJanke SchinkelLieuwe D J Bosnull null

Published in: Intensive care medicine (2024)

In mechanically ventilated COVID-19 patients, HSV reactivations are common, while CMV reactivations were rare. HSV viral load dynamics prior to or without antiviral treatment are associated with mortality. Alveolar inflammation is elevated after HSV reactivation.

Keyphrases

herpes simplex virus
acute respiratory distress syndrome
extracorporeal membrane oxygenation
sars cov
mechanical ventilation
coronavirus disease
oxidative stress
pulmonary hypertension
intensive care unit
cardiovascular disease
smoking cessation