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Recurrent RET gene fusions in paediatric spindle mesenchymal neoplasms.

Jessica L DavisSara O VargasErin R RudzinskiJessica M López MartiKatherine JanewaySuzanne ForrestKatrina WinsnesNavin PintoSung E YangMandy VanSandtTheonia K BoydChristopher L CorlessYajuan J LiuLea F SurreyMarian H HarrisAlanna ChurchAlyaa Al-Ibraheemi
Published in: Histopathology (2020)
Our findings help to define RET-rearranged spindle cell tumours. Although it is likely that these tumours comprise part of the morphological and clinical spectrum of infantile fibrosarcoma (IFS), identification of RET gene alteration is important for its unique therapeutic implications.
Keyphrases
  • copy number
  • genome wide
  • genome wide identification
  • single cell
  • intensive care unit
  • stem cells
  • emergency department
  • bone marrow
  • cell therapy
  • transcription factor