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Capparis Spinosa L. promotes anti-inflammatory response in vitro through the control of cytokine gene expression in human peripheral blood mononuclear cells.

Mouna MoutiaKhadija El AzharyAnass ElouaddariAbdellah Al JahidJamal Jamal EddineFouad SeghrouchniNorddine HabtiAbdallah Badou
Published in: BMC immunology (2016)
Altogether, these findings suggest that our Capparis Spinosa preparation contains interesting compounds, which could be used to suppress IL-17 and to enhance IL-4 gene expression in certain inflammatory situations. Other studies are underway in order to identify the compound(s) underlying this effect.
Keyphrases
  • gene expression
  • inflammatory response
  • dna methylation
  • endothelial cells
  • lipopolysaccharide induced
  • oxidative stress
  • induced pluripotent stem cells
  • toll like receptor
  • case control
  • molecularly imprinted