miR-200c-3p, miR-222-5p, and miR-512-3p Constitute a Biomarker Signature of Sorafenib Effectiveness in Advanced Hepatocellular Carcinoma.
Patricia de la Cruz-OjedaTobias SchmidLoreto BoixManuela MorenoVíctor SapenaJuan M Praena-FernándezFrancisco J CastellJuan Manuel Falcon-PerezMaria ReigBernhard BrüneMiguel Ángel Gómez-BravoÁlvaro Giráldez-GallegoJordi BruixMaría T FerrerJordi MuntanéPublished in: Cells (2022)
The study showed that Sorafenib regulates a specific miRNA signature in which miR-200c-3p, miR-222-5p, and miR-512-3p bear prognostic value and contribute to treatment response.