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Tall-columnar glandular cells in SurePath™ liquid-based cytology Pap sample: Learning from mimics/pitfalls.

Nalini GuptaVanita JainRadhika SrinivasanTulika Singh
Published in: Cytopathology : official journal of the British Society for Clinical Cytology (2024)
We offer a comprehensive depiction of the cytomorphological characteristics of lobular endocervical glandular hyperplasia (LEGH) as observed in SurePath™ liquid-based cytology (LBC), subsequently confirmed on cone biopsy. Lobular endocervical glandular hyperplasia (LEGH), a precursor to gastric-type adenocarcinoma (GAE) of the endocervix, is rare and reports of it in cervical cytology are scarce. We provide a thorough description of the cytomorphological features of LEGH observed in SurePath™ liquid-based cytology (LBC), later confirmed by cone biopsy. To the best of our knowledge, this is the first report documenting cytology of LEGH in LBC of a Pap sample.
Keyphrases
  • fine needle aspiration
  • ultrasound guided
  • high grade
  • ionic liquid
  • healthcare
  • induced apoptosis
  • squamous cell carcinoma
  • emergency department
  • cell cycle arrest
  • cell death