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Detection of a novel single nucleotide polymorphism in IGF2 gene with a negative impact on egg production and body weight in Japanese quail (Coturnix japonica).

Dhafer A AliMohammed Baqur S Al-ShuhaibGolzar FarhadiFadhil R Al-KafajyTahreer M Al-ThuwainiAli Esmailizadeh
Published in: Journal, genetic engineering & biotechnology (2021)
The detected p.F79=SNP has a highly negative effect on EN and BW in Japanese quail. Thus, the implementation of the variations of the IGF2 gene can be a useful marker in the marker-assisted selection of Japanese quail. This is the first report to describe IGF2 gene variations in Japanese quail, which strongly suggests raising the birds from the BR line with AA genotype when breeders desire to raise Japanese quail for large-scale egg production.
Keyphrases
  • genome wide
  • body weight
  • copy number
  • healthcare
  • binding protein
  • genome wide identification
  • primary care
  • pi k akt
  • dna methylation
  • transcription factor
  • growth hormone
  • cell proliferation