Role of glomerular filtration rate-modifying drugs in the development of anticoagulant-related nephropathy.
Ajay K MedipallyMin XiaoBrad H RovinAnjali A SatoskarIouri IvanovShahzeb QaisarSergey V BrodskyPublished in: Physiological reports (2021)
GFR does not play a significant role in the dabigatran-induced acute kidney injury in 5/6 nephrectomy model in rats. Based in these data, modification of GFR in patients with ARN is not warranted.