Evaluation of drug susceptibility profile of Mycobacterium tuberculosis Lineage 1 from Brazil based on whole genome sequencing and phenotypic methods.

Arthur Emil Dos Santos GuimarãesAbhinav SharmaIsmari Perini FurlanetoLiliana RutaihwaJedson Ferreira CardosoMarília Lima da ConceiçãoLizânia Borges SpinasséEdson MachadoMaria Luiza LopesRafael Silva DuarteSebastien GagneuxPhilip Noel SuffysKarla Valéria Batista LimaEmilyn Costa Conceição

Published in: Memorias do Instituto Oswaldo Cruz (2021)

Drug resistance profiling using next-generation sequencing offers rapid assessment of resistance-associated mutations, therefore facilitating rapid access to effective treatment.

Keyphrases

mycobacterium tuberculosis
single cell
copy number
gene expression
emergency department
pulmonary tuberculosis
circulating tumor
electronic health record