Development of a multi-component gastroretentive expandable drug delivery system (GREDDS) for personalized administration of metformin.
Marco UboldiArianna ChiappaMargherita RossiFrancesco Briatico-VangosaAlice MelocchiLucia ZemaPublished in: Expert opinion on drug delivery (2023)
Composition, geometry and performance of the system developed in this work were deemed acceptable for stomach retention and prolonged as well as customizable release of metformin at its absorption window, laying promising bases for further development steps.
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