The impact of anti-TNF treatment on Wnt signaling, noggin, and cytokine levels in axial spondyloarthritis.
Nuh AtasBağdagül ÇakırFatih BakırMurat UçarHasan SatışGizem Tuğçe GüzKübra Durmuş DemirelHakan BabaoğluReyhan Bilici SalmanAslıhan Avanoğlu GülerHazan KaradenizŞeminur HaznedaroğluBerna GökerMehmet Akif ÖztürkAbdurrahman TufanPublished in: Clinical rheumatology (2022)
• Anti-TNF therapy is not sufficient for complete blockage of the inflammatory process in axial spondyloarthritis. • The increase in IL-17, IL-22, and IL-33 may decrease the efficiency of anti-TNF therapy. • Noggin might be a therapeutic target as a complementary or alternative approach to anti-TNF therapy in axial spondyloarthritis.