Direct C-H functionalization of difluoroboron dipyrromethenes (BODIPYs) at β-position by iodonium salts.
Wenming RenHuaijiang XiangChengyuan PengZulipali MushaJingjing ChenXin LiRuimin HuangYou-Hong HuPublished in: RSC advances (2018)
A copper-catalyzed direct C-H arylation or vinylation of BODIPYs at the β-position by iodonium salts has been developed, which provides facile access to a variety of mono-substituted BODIPY dyes. Interestingly, β-styryl BODIPY compound 9b exhibits apparent cytotoxicity after laser irradiation, which has great potential for photodynamic therapy.
Keyphrases
- photodynamic therapy
- fluorescent probe
- living cells
- ionic liquid
- molecular docking
- fluorescence imaging
- diffusion weighted imaging
- human health
- magnetic resonance
- magnetic resonance imaging
- radiation therapy
- radiation induced
- climate change
- high resolution
- risk assessment
- mass spectrometry
- metal organic framework
- contrast enhanced