Transcriptome analysis of sevoflurane exposure effects at the different brain regions.

Hiroto YamamotoYutaro UchidaTomoki ChibaRyota KurimotoTakahide MatsushimaMaiko InotsumeChihiro IshikawaHaiyan LiTakashi ShigaMasafumi MurataniTokujiro UchidaTokujiro Uchida

Published in: PloS one (2020)

Klf4 was upregulated by sevoflurane inhalation in the mouse brain. The roles of KLF4 might be key to elucidating the mechanisms of sevoflurane induced functional modification in the brain.

Keyphrases

resting state
white matter
transcription factor
functional connectivity
high glucose
diabetic rats
drug induced
endothelial cells
oxidative stress