Effects of melatonin prolonged-release on both sleep and motor symptoms in Parkinson's disease: a preliminary evidence.

Claudio Liguori Mariana FernandesRocco CerroniRaffaella LudovisiNicola Biagio MercuriAlessandro StefaniMariangela Pierantozzi

Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2022)

These findings suggest that melatonin may improve sleep symptoms in PD patients, although further evidence is needed in larger controlled studies to confirm these results and explore the possible direct and indirect influence of sleep improvement on motor dysfunction.

Keyphrases

sleep quality
end stage renal disease
physical activity
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
prognostic factors
oxidative stress
depressive symptoms