Mitochondrial perturbation in immune cells enhances cell-mediated innate immunity in Drosophila.
Laura VesalaYuliya BasikhinaTea TuomelaAnssi NurminenEmilia SiukolaPedro F ValeTiina S SalminenPublished in: BMC biology (2024)
Overall, we show that while the effects of mitochondrial perturbation on immune responses are highly tissue-specific, mild mitochondrial dysfunction can be beneficial in immune-challenged individuals and contributes to variation in infection outcomes among individuals.