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Genetic generalized epilepsies with frontal lesions mimicking migratory disorders on the epilepsy monitoring unit.

Susanne FauserThomas CloppenborgTilman PolsterUlrich SpechtFriedrich G WoermannChristian G Bien
Published in: Epilepsia open (2020)
Patients with GGE may have coincidental MRI abnormalities. These cases are challenging as frontal epilepsy and GGE can present with similar semiologies. GGE with coincidental FCD-like lesions/heterotopias is in particular difficult to diagnose as patients have more lateralizing features (in semiology and EEG) than those with tumors. A detailed noninvasive presurgical evaluation may be justified. We point out red flags that may help to distinguish GGE from frontal epilepsy, even in the presence of brain abnormalities: 3/s spike waves (even if asymmetric), changing lateralizing signs at different times, and a positive family history hinting at GGE.
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