Nickel-Catalyzed 3,3-Dialkynylation of 2-Aryl Acrylamides: Direct Access to gem-Diethynylethenes via Double Vinylic C-H Bond Activation.

Direct access to gem-diethynylethenes is achieved by a Ni-catalyzed 3,3-dialkynylation of 2-aryl acrylamides with 1-bromotriisopropylsilylacetylene. The preliminary mechanism study reveals that the reaction goes through a sequential double vinylic C-H bond activation with the assistance of an 8-aminoquinolinyl directing group.