Influences of experimental parameters on chemical exchange saturation transfer (CEST) metrics of brain tumors using animal models at 4.7T.

Tumor MTRasym (3.5 ppm), APT# , and NOE# contrasts can be maximized at different saturation parameters. The maximum MTRasym (3.5 ppm) contrast can be obtained with a relatively longer RF saturation length (several seconds) at a relatively lower RF saturation power.